Samuel H. Gellman, PhD
Immunology Focus area: Manipulation of polypeptide recognition by T cells; targeted induction of tolerance
Descriptive Title of Research: Organic chemistry, chemical biology, peptide and protein chemistry
Research Description: Current topics include: the design of new oligomers with well-defined folding properties (“foldamers”), and their use for antimicrobial applications, for inhibition of protein-protein interactions, for modulation of GPCR-mediated signaling and for other biomedical applications; the origins of protein conformational preferences; new amphiphiles for membrane protein solubilization and crystallization; synthesis and applications of poly-beta-peptides (nylon-3 materials).
Graduate Program Affiliations: Chemistry, Biochemistry, Biophysics
Lab Website: gellman.chem.wisc.edu