Jenny Gumperz, PhD
Medical Microbiology & Immunology
Department: Medical Microbiology and Immunology
Immunology Focus area: Innate T lymphocytes, cancer immunotherapy and immunoprevention, hematopoietic transplantation, humanized mouse models
Descriptive Title of Research: Understanding the activation and functions of innate T lymphocytes
Research Description: Research in the Gumperz lab focuses on understanding the molecular recognition strategies and immunological functions of human innate lymphocytes such as natural killer T (NKT) cells, mucosal-associated invariant T (MAIT) cells, and gd T cells. The goal of our studies is to develop novel and readily translatable immunotherapeutic approaches utilizing the unique features of innate T lymphocytes. We thus focus on developing and using pre-clinical “humanized” mouse experimental systems to investigate the functions and interactions of human immune cells in vivo, and to assess their impact on cancer and hematopoietic transplantation.
Link to Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=gumperz+j
Lab Website: https://labs.medmicro.wisc.edu/gumperz/Gumperz_Lab/Home.html