Jenny Gumperz, PhD

Biography

Department: Medical Microbiology and Immunology Immunology Focus area: Innate T lymphocytes, cancer immunotherapy and                                                                                                                       immunoprevention, hematopoietic transplantation, humanized mouse models Descriptive Title of Research: Understanding the activation and functions of innate T lymphocytes Research Description:  Research in the Gumperz lab focuses on understanding the molecular recognition strategies and immunological functions of human innate lymphocytes such as natural killer T (NKT) cells, mucosal-associated invariant T (MAIT) cells, and gd T cells.  The goal of our studies is to develop novel and readily translatable immunotherapeutic approaches utilizing the unique features of innate T lymphocytes.  We thus focus on developing and using pre-clinical “humanized” mouse experimental systems to investigate the functions and interactions of human immune cells in vivo, and to assess their impact on cancer and hematopoietic transplantation. Link to Publications:  https://www.ncbi.nlm.nih.gov/pubmed/?term=gumperz+j Graduate Program Affiliations:  CBMS, CMP, ICTR, MDTP, MSTP Lab Website:  https://labs.medmicro.wisc.edu/gumperz/Gumperz_Lab/Home.html