Position title: Assistant Professor, Department of Pediatrics
Immunology Focus Area: Mucosal Immunology, Epithelial-Immune Interactions, Microbiome
Descriptive Title of Research: Inflammatory Control in the Gastrointestinal Tract
Research Description: The O’Leary lab is studying how gastrointestinal tissues restrain immune activation in the face of harsh environments, while also retaining the capacity for a rapid response to pathogens. We are focused on how rare cells, called tuft cells, in the single cell epithelial barrier lining the gastrointestinal tract coordinate defensive and protective responses to changing conditions, including microbial metabolites.
Graduate Program Affiliations: Cell and Molecular Biology, Cell and Molecular Pathology, Microbiology Doctoral Training Program