Lixin Rui, PhD

Biography

Department:      Medicine Immunology Focus area: B cell lymphoma and biology Descriptive Title of Research: B cell receptor and JAK-STAT signaling in B cell lymphoma Research Description:The major research interest in Dr. Rui’s laboratory is the mechanisms of the B cell receptor (BCR) and JAK-STAT signaling pathways in lymphomagenesis. His research team employs a multidisciplinary approach, using biochemistry, RNA interference, next-generation sequencing (including ChIP-seq and RNA-seq), CRISPR/Cas9 and systems biology methods, to identify target genes downstream of BCR and JAK-STAT signaling in B cell lymphoma. The goal of his research is to discover effective molecular targets in these pathways for therapeutic, diagnostic and prognostic development of B cell lymphoma. Link to Publications: https://www.ncbi.nlm.nih.gov/sites/myncbi/12CH-2wLplkAf/bibliography/44961547/public/?sort=date&direction=descending Graduate Program Affiliations:

• Cellular and Molecular Biology
• Cellular and Molecular Pathology
• Cancer Biology
• Molecular and Cellular Pharmacology

Lab Website: http://www.medicine.wisc.edu/hemonc/rui-lab