Lixin Rui, PhD

Position title: Medicine


Department:      Medicine

Immunology Focus area: B cell lymphoma and biology

Descriptive Title of Research: B cell receptor and JAK-STAT signaling in B cell lymphoma

Research Description:The major research interest in Dr. Rui’s laboratory is the mechanisms of the B cell receptor (BCR) and JAK-STAT signaling pathways in lymphomagenesis. His research team employs a multidisciplinary approach, using biochemistry, RNA interference, next-generation sequencing (including ChIP-seq and RNA-seq), CRISPR/Cas9 and systems biology methods, to identify target genes downstream of BCR and JAK-STAT signaling in B cell lymphoma. The goal of his research is to discover effective molecular targets in these pathways for therapeutic, diagnostic and prognostic development of B cell lymphoma.

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