Department: Biomedical Engineering
Immunology Focus area: Cell Therapy Manufacturing
Descriptive Title of Research: Genome Editing and Engineering
Research Description: We utilize quantitative and bioengineering methods to advance the next generation of cell and gene therapies. Cells are living drugs that can be difficult to generate, scale-up, and quality control. Projects include monitoring and controlling the heterogeneity during gene modification and scale-up of stem cells and T cell immunotherapies (e.g., CAR T cells). We benefit from collaborations with the national Center for Cell Manufacturing.
Link to Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=Krishanu+Saha+or+Kris+Saha
Graduate Program Affiliations: Biomedical Engineering, Genome Sciences Training Program, Cellular and Molecular Biology
Lab Website: https://sahalab.bme.wisc.edu/