University of Wisconsin - Madison
Biography Department: Department of Medicine, Division of Nephrology Immunology Focus area: Transplant Immunology, glomerulonephritis, B cells Descriptive Title of Research: Preventing failure of kidney transplants: identifying novel immunologic mechanisms through translational research Research Description: Our research group focuses on the study of immune-mediated kidney injury and chronic antibody mediated rejection through translational research. We …
Biography Department: Pediatrics (Division of Pediatric Hematology, Oncology, and Bone Marrow Transplant) Immunology Focus area: Immunotherapy, CAR-T cells Descriptive Title of Research: Developing next-generation CAR-T cells for treatment of AML Research Description: The Richards lab focuses on developing chimeric antigen receptor T (CAR-T) cell therapy for acute myeloid leukemia (AML), a disease that …
Biography Department: Biomedical Engineering Immunology Focus area: Cell Therapy Manufacturing Descriptive Title of Research: Genome Editing and Engineering Research Description: We utilize quantitative and bioengineering methods to advance the next generation of cell and gene therapies. Cells are living drugs that can be difficult to generate, scale-up, and quality control. Projects include monitoring and controlling the …
Biography Department: Medicine Immunology Focus area: Autoimmunity and Basic Immunology Descriptive Title of Research: Understanding Immunity, Inflammation and Autoimmunity Research Description: Dr. Miriam Shelef is a rheumatologist and an immunologist with a laboratory focused on immunity, inflammation, and rheumatoid arthritis in order to improve diagnostics and treatment. Her early work defined the requirement for Blimp-1 …
Biography Department: Pediatrics Immunology Focus area: Host-Pathogen interaction Descriptive Title of Research: Host-Pathogen interaction and ER stress Research Description: Overall theme: The endoplasmic reticulum stress response known as the “Unfolded Protein Response” (UPR) has been implicated in such diverse processes as viral infection, cancer, neurodegenerative disease, autoimmune diseases, diabetes and cardiovascular disease. In our lab, …
Biography Department: Obstetrics and Gynecology (Div. Reproductive Sciences, Reproductive Endocrinology and Infertility) Immunology Focus area: Pregnancy and Reproductive Immunology Descriptive Title of Research: Deciphering the role of immune cellular and molecular networks in the growth and architectural organization of the maternal/fetal interface Research Description: We are dedicated to discovery of cellular networks necessary for …
Biography Department: Medicine Immunology Focus area: Adaptive Immunity Descriptive Title of Research: How the Balance between CD4 and CD8 T Cells is Maintained and Altered by Infections and Aging Research Description: The immune system’s functions are altered by whether or not it is in homeostasis, and whether or not it can return to a balance …
Biography Department: Comparative Biosciences Immunology Focus area: Neuroimmunology, innate immunity, epigenetic regulation of transcription and immune cell memory Descriptive Title of Research: Mechanisms of microglial regulation by hypoxia, and their role in neuroplasticity Research Description: Signal transduction and transcriptional regulation in microglia Regulation of microglial immune activities by paradigms of hypoxia Epigenetic modulation …