Biography Department: Oncology Immunology Focus area: Preparation and use of mAbs in biochemical research, gentle immunoaffinity chromatography, immunochemistry, large-scale mAb purification, use of mAb affinity magnetic beads to isolate weakly bound protein complexes to identify new drug discovery targets. Descriptive Title of Research: Just recently was awarded a 2-year SBIR grant with Salus Discovery LLC; …
Biography Department: Medicine Immunology Focus area: Mucosal Immunity Descriptive Title of Research: P2X7-regulation of oyxlipin metabolism during virus induced exacertbations of asthma Research Description: The Denlinger lab studies the roles of extracellular nucleotides as paracrine stress hormones. One specific project centers on a nucleotide receptor P2X7 and its role in amplifying innate immune responses to …
Biography Department: Oncology and Biostatistics & Medical Informatics (BMI) Immunology Focus area: Tumor Immunology, Basic Immunology Descriptive Title of Research: Defining myeloid cell heterogeneity and plasticity in inflammation and cancers Research Description: Cancer is a heterogeneous disease that complicates its study and, therefore, treatment. Immunotherapy has revolutionized cancer treatment, but many patients still are faced …
Biography Department: Chemistry Immunology Focus area: Manipulation of polypeptide recognition by T cells; targeted induction of tolerance Descriptive Title of Research: Organic chemistry, chemical biology, peptide and protein chemistry Research Description: Current topics include: the design of new oligomers with well-defined folding properties (“foldamers”), and their use for antimicrobial applications, for inhibition of protein-protein …
Biography Department: Medical Microbiology and Immunology Immunology Focus area: Innate T lymphocytes, cancer immunotherapy and immunoprevention, hematopoietic transplantation, humanized mouse models Descriptive Title of Research: Understanding the activation and functions of innate T lymphocytes Research Description: Research in the Gumperz lab focuses on understanding the molecular recognition strategies and immunological functions of human …
Biography Name: Anna Huttenlocher, MD Department: Medical Microbiology and Immunology Immunology Focus Area: Autoimmunity, Reproductive, and Transplant Immunology Descriptive Title of Research: Innate immunity and inflammation Research Description: The focus of research in our group is on understanding the molecular mechanisms that regulate inflammation and its resolution. Using both human cells (primary …
Biography Immunology Focus Area: Mucosal Immunology, Epithelial-Immune Interactions, Microbiome Descriptive Title of Research: Inflammatory Control in the Gastrointestinal Tract Research Description: The O’Leary lab is studying how gastrointestinal tissues restrain immune activation in the face of harsh environments, while also retaining the capacity for a rapid response to pathogens. We are focused on how rare cells, …
Biography Name: M. Suresh, DVM, PhD Department: Pathobiological Sciences Immunology Focus area: Basic Immunology Descriptive Title of Research: Mechanisms of T-Cell Memory and Protective Immunity to Intracellular Pathogens Research Description: Establishment and maintenance of protective memory B and T cells is fundamental to the development of effective vaccines. To date, protection afforded by …
Biography Immunology Focus area: Basic Immunology Descriptive Title of Research: Laryngeal and Upper Airway Immunology Research Description: My research has focused on translational and clinical investigations of laryngeal disorders. Main areas of focus in my research laboratory tissue regeneration of vocal fold mucosa, laryngeal development, microbiology and immunology. Link to Publications: https://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&term=thibeault+sl%5BAuthor+Name%5D+OR+(thibeault+s%5Bauth%5D+AND+(madison%5Baffl%5D+OR+salt+lake+city%5Baffl%5D) Graduate Program Affiliations: …
Biography Department: Pathology and Laboratory Medicine Immunology Focus area: Neuroimmunology of Neurodegenerative Diseases Descriptive Title of Research: Determining the Role of the Innate Immune Response in AD Research Description: Research in the Ulland Lab is focused on gaining a deeper understanding of the mechanisms, including metabolic and transcriptional changes, which govern the innate immune …